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J Allergy Clin Immunol. 2009 Dec;124(6 Suppl):S88-93. doi: 10.1016/j.jaci.2009.09.050.

Particle size of inhaled corticosteroids: does it matter?

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1
Lovelace Respiratory Research Institute, Albuquerque, NM, USA.

Abstract

A question with respect to asthma therapy revolves around the issue of whether better efficacy occurs with an ultrafine-particle inhaled corticosteroid because of better lung deposition into the distal airways. This article reviews particle size and delivery devices of different steroids, clinical outcomes of small- versus large-particle steroids, and the issue of pharmacoeconomics.

PMID:
19962042
DOI:
10.1016/j.jaci.2009.09.050
[Indexed for MEDLINE]

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