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Emerg Infect Dis. 2009 Dec;15(12):1988-90. doi: 10.3201/eid1512.090928.

CTX-M beta-lactamase production and virulence of Escherichia coli K1.

Author information

1
University of Auvergne, Clermont-Ferrand F-63001, France.

Abstract

We report a patient with neonatal meningitis caused by a CTX-M-1-producing Escherichia coli K1 strain. The influence of CTX-M production on virulence was investigated in cell culture and a newborn mouse model of meningitis. CTX-M production had no influence on virulence but was a major factor in clinical outcome.

PMID:
19961682
PMCID:
PMC3044546
DOI:
10.3201/eid1512.090928
[Indexed for MEDLINE]
Free PMC Article

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