Send to

Choose Destination
See comment in PubMed Commons below
Int J Pediatr Endocrinol. 2009;2009:487804. doi: 10.1155/2009/487804. Epub 2009 Sep 17.

Reliable prediction of insulin resistance by a school-based fitness test in middle-school children.

Author information

  • 1Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, H4/4 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792-4108, USA.


Objectives. (1) Determine the predictive value of a school-based test of cardiovascular fitness (CVF) for insulin resistance (IR); (2) compare a "school-based" prediction of IR to a "laboratory-based" prediction, using various measures of fitness and body composition. Methods. Middle school children (n = 82) performed the Progressive Aerobic Cardiovascular Endurance Run (PACER), a school-based CVF test, and underwent evaluation of maximal oxygen consumption treadmill testing (VO(2) max), body composition (percent body fat and BMI z score), and IR (derived homeostasis model assessment index [HOMA(IR)]). Results. PACER showed a strong correlation with VO(2) max/kg (r(s) = 0.83, P < .001) and with HOMA(IR) (r(s) = -0.60, P < .001). Multivariate regression analysis revealed that a school-based model (using PACER and BMI z score) predicted IR similar to a laboratory-based model (using VO(2) max/kg of lean body mass and percent body fat). Conclusions. The PACER is a valid school-based test of CVF, is predictive of IR, and has a similar relationship to IR when compared to complex laboratory-based testing. Simple school-based measures of childhood fitness (PACER) and fatness (BMI z score) could be used to identify childhood risk for IR and evaluate interventions.

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Support Center