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Eur J Surg Oncol. 2010 Apr;36(4):335-9. doi: 10.1016/j.ejso.2009.11.006. Epub 2009 Dec 1.

Aggressive angiomyxoma: a case series and literature review.

Author information

1
Oxford Cancer Centre, Department of Gynaecologic Oncology, Churchill Hospital, Old Road, Oxford OX3 7LJ, United Kingdom. krishnayan_haldar@yahoo.com

Abstract

BACKGROUND:

Aggressive angiomyxoma was identified as a distinct clinicopathologic entity in 1983 and since then fewer than 250 cases of these rare tumors have been reported in world literature. These tumors usually arise in the pelvis and perineal regions, most often in women of the reproductive age group; however a few cases of its occurrence outside the pelvis have also been reported.

PATIENTS AND METHODS:

We report a series of 7 women treated in our institute in the last 8 years. Relevant literature on aggressive angiomyxoma was looked at and various management options reviewed.

CONCLUSION:

Aggressive angiomyxomas are locally aggressive, notorious for local recurrence and extremely rare to metastasize. While surgery remains the mainstay of treatment, there has been a definite shift towards less radical forms of excision, over the years. Various adjuvant treatment modalities have also been tried to reduce tumor recurrence.

PMID:
19954923
DOI:
10.1016/j.ejso.2009.11.006
[Indexed for MEDLINE]

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