Format

Send to

Choose Destination
Am J Ind Med. 2010 Jan;53(1):42-6. doi: 10.1002/ajim.20786.

Occupational immediate-type asthma and rhinitis due to rhodium salts.

Author information

1
Research Institute of Occupational Medicine, German Social Accident Insurance (BGFA), Ruhr University, B├╝rkle-de-la-Camp-Platz 1, Bochum, Germany. merget@bgfa.de

Abstract

BACKGROUND:

Whereas platinum salts are well known occupational allergens, rhodium salts have not been identified as inhalative sensitizing substances.

METHODS:

A 27-year-old atopic operator of an electroplating plant developed work-related shortness of breath and runny nose with sneezing after exposure to rhodium salts. Quantitative skin prick tests (SPT) and bronchial challenge tests with a dosimeter protocol were performed with quadrupling doses of the sodium chloride salts of rhodium (Na(3)RhCl(6)) and platinum (Na(2)PtCl(6)).

RESULTS:

The patient showed positive SPT reactions and positive bronchial immediate-type reactions with rhodium and platinum salts. Sensitivity to rhodium salt was much higher than to platinum salt; the molar concentrations differed by a factor of 256 in SPT and a factor of 16 in bronchial challenges.

CONCLUSIONS:

Rhodium salts should be considered as occupational immediate-type allergens.

PMID:
19953567
DOI:
10.1002/ajim.20786
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center