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Clin Infect Dis. 2010 Jan 1;50(1):73-6. doi: 10.1086/648727.

Increasing incidence of post-kala-azar dermal leishmaniasis in a population-based study in Bangladesh.

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International Centre for Diarrhoeal Disease Research, Bangladesh.

Erratum in

  • Clin Infect Dis. 2010 May 1;50(9):1329. Galive, Chowdhury Mohammad [corrected to Ghalib, Chowdhury Mohammad].


Post-kala-azar dermal leishmaniasis (PKDL) occurs after kala-azar treatment and acts as a durable infection reservoir. On the basis of active case finding among 22,699 respondents, 813 (3.6%) had had kala-azar since 2002, of whom 79 (9.7%) developed PKDL. Eight additional patients with PKDL had no history of kala-azar. Annual kala-azar incidence peaked at 85 cases per 10,000 person-years in 2004 and fell to 46 cases per 10,000 person-years in 2007, but PKDL incidence rose from 1 case per 10,000 person-years in 2002-2004 to 21 cases per 10,000 person-years in 2007. The rising PKDL incidence threatens the regional visceral leishmaniasis elimination initiative and underscores the urgent need for more effective PKDL diagnosis and treatment.

[Indexed for MEDLINE]

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