Send to

Choose Destination
See comment in PubMed Commons below
Clin Perinatol. 2009 Dec;36(4):723-36, v. doi: 10.1016/j.clp.2009.07.015.

Systemic and cerebral hemodynamics during the transitional period after premature birth.

Author information

Section of Neonatal-Perinatal Medicine, Department of Pediatrics, The Children's Hospital, College of Medicine, The University of Oklahoma Health Sciences Center, 1200 Everett Drive, Oklahoma City, OK 73104-5047, USA.


Little is known about the effect on clinically relevant outcomes of the complex hemodynamic changes occurring during adaptation to extrauterine life in preterm neonates, particularly in very low birth weight neonates. As cardiovascular adaptation in this extremely vulnerable patient population is complicated by immaturity of all organ systems, especially that of the cardiorespiratory, central nervous, and endocrine systems, maladaptation has been suspected, but not necessarily proven, to contribute to mortality and long-term morbidities. This article describes recent advances in the understanding of hemodynamic changes in very low birth weight neonates during postnatal transition, and reviews the complex and developmentally regulated interaction between systemic and cerebral hemodynamics and the effect of this interaction on clinically relevant outcomes.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center