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Heart Fail Rev. 2010 Jan;15(1):103-7. doi: 10.1007/s10741-009-9156-8.

Cardiomyopathy in Duchenne muscular dystrophy: pathogenesis and therapeutics.

Author information

1
University of Medicine and Dentistry of New Jersey, Camden, NJ, USA. fayssoil2000@yahoo.fr

Abstract

Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder caused by the absence of dystrophin, a sarcolemmal protein which links the cytoskeleton to the extracellular matrix by interacting with a large number of proteins. Heart failure is a classic complication of this disease. The authors review the pathogenesis and therapeutics of cardiac involvement in DMD.

PMID:
19943106
DOI:
10.1007/s10741-009-9156-8
[Indexed for MEDLINE]

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