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Arq Bras Endocrinol Metabol. 2009 Oct;53(7):844-52.

[Serum chemistry test and urinalysis parameter analysis in half marathon athletes].

[Article in Portuguese]

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Curso de Farmácia, Instituto de Ciências Biológicas, Universidade de Passo Fundo, Passo Fundo, RS, Brasil.



The aim of this study was to analyze biochemical markers as indicators of athletic performance, in light of a clinical context and athletic.


Samples of peripheral blood (8 mL) and urine (50 mL) were collected from 20 marathon athletes at rest and 15 minutes after half marathon. Following, examination of blood, urine and serum markers of renal function, muscle damage and lipidic profile was carried out.


Statistical analysis of the results showed a significant increase (p < 0.05) in serum activity of the enzymes CK, CK-MM, CK-MB and LDH, serum creatinine and iron, leukocyte count and neutrophils. Furthermore, triglycerides, VLDL, uric acid in serum showed a significant decrease.


This study shows that athletes of marathon show changes in biochemical parameters of blood and urine after competing in this modality, which demonstrates the importance of carrying out laboratory tests as diagnosis for silent biochemical disorders.

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