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Cell Mol Biol Lett. 2010;15(1):90-7. doi: 10.2478/s11658-009-0036-y. Epub 2009 Nov 20.

The antioxidant properties of carnitine in vitro.

Author information

1
Department of Biochemistry and Cell Biology, University of Rzeszów, Pigonia 6, 35-959, Rzeszów, Poland.

Abstract

Many of the effects of carnitine are ascribed to its antioxidant properties. The aim of this study was to evaluate the antioxidant properties of carnitine in vitro. Carnitine was found to decolorize ABTS(*+), and to protect fluorescein against bleaching induced by AAPH-derived peroxyl radicals and peroxynitrite, thiol groups against oxidation induced by hydrogen peroxide, peroxyl radicals, hypochlorite and peroxynitrite, and erythrocytes against hemolysis induced by peroxyl radicals and hypochlorite. These results show that carnitine has a direct antioxidant action against physiologically relevant oxidants.

PMID:
19936630
PMCID:
PMC6275708
DOI:
10.2478/s11658-009-0036-y
[Indexed for MEDLINE]
Free PMC Article

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