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Bioorg Med Chem Lett. 2010 Jan 1;20(1):180-3. doi: 10.1016/j.bmcl.2009.11.004. Epub 2009 Nov 10.

Novel lead for potent inhibitors of breast cancer resistance protein (BCRP).

Author information

1
Pharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany.

Abstract

From our modulator library an interesting inhibitor of breast cancer resistance protein (BCRP) was identified. Due to its high inhibitory potency, this compound may serve as a promising novel lead for the design of new and potent modulators. This adds a new structural class to the few known highly active BCRP inhibitors.

PMID:
19932960
DOI:
10.1016/j.bmcl.2009.11.004
[Indexed for MEDLINE]

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