Format

Send to

Choose Destination
See comment in PubMed Commons below
Expert Rev Proteomics. 2009 Dec;6(6):631-45. doi: 10.1586/epr.09.82.

Glycan array: a powerful tool for glycomics studies.

Author information

1
The Genomics Research Center, Academia Sinica, 128 Academia Road, Section 2, Nankang, Taipei, 115, Taiwan. jamesl@gate.sinica.edu.tw

Abstract

Glycan arrays have become a powerful tool for the high-throughput elucidation of interactions of different carbohydrate structures with a wide variety of biological targets, including antibodies, proteins, viruses and cells. This technique is especially suitable for glycomics studies, because arrays present carbohydrate ligands in a manner that mimics interactions at cell-cell interfaces. This review assesses the recent advances involving glycan arrays, including new methods for glycan-array fabrication, new platforms for novel biological information, and new perceptions of glycomics for improving the understanding of disease-related glycobiology. Furthermore, this review attempts to forecast trends in the development of glycan arrays and possible solutions for some remaining challenges to improve this new technology.

PMID:
19929609
DOI:
10.1586/epr.09.82
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis
    Loading ...
    Support Center