Format

Send to

Choose Destination
See comment in PubMed Commons below
J Pediatr (Rio J). 2010 Jan-Feb;86(1):85-8.doi:10.2223/JPED.1948. Epub 2009 Nov 16.

Congenital toxoplasmosis from a chronically infected woman with reactivation of retinochoroiditis during pregnancy.

Author information

1
Departamento de Pediatria, Núcleo de Apoio em Pesquisa e Apoio Diagnóstico (NUPAD), Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil. qandrade.bh@terra.com.br

Abstract

OBJECTIVE:

To report a rare case of congenital toxoplasmosis from an immunocompetent mother with chronic infection who had reactivation of ocular disease during pregnancy.

DESCRIPTION:

The newborn was asymptomatic at birth and identified by neonatal screening (IgM anti-Toxoplasma gondii in dried blood) among other 190 infants with congenital toxoplasmosis during a 7-month period. His mother had had a non-treated episode of reactivation of toxoplasmic retinochoroiditis during pregnancy, with stable IgG titers and negative IgM results. Results of IgM and IgG in the newborn's serum, as well as IgG immunoblotting were positive and active retinochoroidal lesions were detected in his peripheral retina. The neonate was treated with sulfadiazine, pyrimethamine and folinic acid. At 14 months of life, the child remained asymptomatic, with regression of retinochoroidal lesions and persistence of IgG.

COMMENTS:

It is possible that systematic neonatal screening in areas with high prevalence of infection may identify these cases.

PMID:
19918624
DOI:
doi:10.2223/JPED.1948
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Sociedade Brasileira de Pediatria
    Loading ...
    Support Center