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Mol Cell. 2009 Nov 13;36(3):349-50. doi: 10.1016/j.molcel.2009.10.022.

A PAR-SUMOnious mechanism of NEMO activation.

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1
Molecular and Cellular Pharmacology Program, Medical Scientist Training Program, Department of Pharmacology, University of Wisconsin, Madison, 6159 Wisconsin Institute for Medical Research, Madison, WI 53705, USA.

Abstract

In this issue of Molecular Cell, Stilmann et al. (2009) demonstrate a new mode of prosurvival NF-kappaB activation through the formation of a PARP-1-poly(ADP-ribose) signaling scaffold in response to DNA damage.

PMID:
19917242
DOI:
10.1016/j.molcel.2009.10.022
[Indexed for MEDLINE]
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