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Behav Brain Res. 2010 Mar 17;208(1):270-3. doi: 10.1016/j.bbr.2009.11.014. Epub 2009 Nov 13.

Effects of acute amphetamine exposure on two kinds of Pavlovian approach behavior.

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1
Department of Psychology, Winona State University, Winona, MN 55987, USA. jholden@winona.edu

Abstract

Two kinds of Pavlovian conditioned approach behavior are possible: approach of the CS (sign-tracking) and approach of the US (goal-tracking). We hypothesized that administration of AMP would increase sign-tracking and decrease goal-tracking. However, increasing doses of AMP (up to 2.0mg/kg) decreased measures of sign-tracking while simultaneously increasing measures of goal-tracking. Administration of AMP may shift responding from cues distant from the CS to cues closer to the CS.

PMID:
19914298
PMCID:
PMC2822088
DOI:
10.1016/j.bbr.2009.11.014
[Indexed for MEDLINE]
Free PMC Article
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