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Vaccine. 2011 Apr 18;29(18):3507-10. doi: 10.1016/j.vaccine.2009.10.106. Epub 2009 Nov 10.

Measles vaccine adverse events reported in the mass vaccination campaign of Sichuan province, China from 2007 to 2008.

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  • 1Department of Paediatrics, West China Second Hospital, Sichuan University, Chengdu, Sichuan 610041, China.


The aim of this study was to characterize the adverse events of attenuated measles vaccine in mainland China. We carried out prospective follow-up of adverse events after mass measles immunization practices, categorizing them into two groups: allergic reactions and serious adverse events. The incidence of anaphylaxis reaction was estimated to be 6.5 per million for attenuated measles vaccine. Among 14.3 million vaccination practices, 1 case each of acute disseminated encephalomyelitis (ADEM) and idiopathic thrombocytopenic purpura (ITP) and 28 cases of Henoch-Schonlein purpura (HSP) were reported. The total incidence of serious adverse events after vaccination was 2.14 per million doses.

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