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Fitoterapia. 2010 Jul;81(5):367-70. doi: 10.1016/j.fitote.2009.11.003. Epub 2009 Nov 10.

A new cytotoxic flavonoid from the fruit of Sinopodophyllum hexandrum.

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1
Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing, China.

Abstract

Constituents of the fruit of Sinopodophyllum hexandrum (Royle) Ying (Sinopodophylli Fructus) were investigated. A new flavonoid, 8,2'-diprenylquercetin 3-methyl ether along with 9 known compounds were isolated and identified. Among them, the new compound 8,2'-diprenylquercetin 3-methyl ether exhibited cytotoxic activities against MDA-231 and T47D breast cancer cell lines, quercetin, kaempferol and rutin were isolated from Sinopodophylli Fructus for the first time.

PMID:
19909799
DOI:
10.1016/j.fitote.2009.11.003
[Indexed for MEDLINE]
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