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J Proteome Res. 2010 Jan;9(1):620-5. doi: 10.1021/pr900713u.

MRMaid-DB: a repository of published SRM transitions.

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Bioinformatics Group, Building 63, Cranfield University, Cranfield, Bedfordshire, UK.


Selected reaction monitoring (SRM) is a technique that applies tandem mass spectrometry to quantify specific proteins of biological interest. The key to SRM is finding the best peptide-to-product ion transitions to monitor. The MRMaid database (MRMaid-DB) is a new online database for capturing SRM transitions from published research papers to save practitioners time when searching for transitions that have been previously validated. It contains all the information needed to reproduce the transitions, such as information on the sample matrix, HPLC, and MS instrumentation used, and also includes details of the manuscript of origin. Transitions are submitted using simple Web-based data entry forms, meaning researchers have a simple way to increase access to their transitions, and in turn, may increase the citations for their research papers. MRMaid-DB is free to use, via the Web at .

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