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J Asthma. 2009 Nov;46(9):961-6. doi: 10.3109/02770900903229677.

Serial lung function variability using four portable logging meters.

Author information

1
Occupational Lung Disease Unit, Department of Respiratory Medicine, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UK. vicky.c.moore@heartofengland.nhs.uk

Abstract

OBJECTIVE:

Portable lung function logging meters that allow measurement of peak expiratory flow (PEF) and forced expiratory volume in 1 second (FEV(1)) are useful for the diagnosis and exclusion of asthma. The aim of this study was to investigate the within and between-session variability of PEF and FEV(1) for four logging meters and to determine the sensitivity of meters to detect FEV(1) and PEF diurnal changes.

METHODS:

Thirteen assessors (all hospital staff members) were asked to record 1 week of 2-hour PEF and FEV(1) measurements using four portable lung function meters. Within-session variability of PEF and FEV(1) were compared for each meter using a coefficient of variation (COV). Between-session variability was quantified using parameter estimates from a cosinor analysis which modeled diurnal change for both lung function measures and also allowed for variation between days for individual sessions.

RESULTS:

The mean within-session COV for FEV(1) was consistently lower than that for PEF (p < 0.001). PEF showed a higher but not significantly different (p = 0.068) sensitivity for detecting diurnal variation than FEV(1). PEF was also slightly more variable between days, but not significantly different than FEV(1) (p = 0.409). PEF and FEV(1) diurnal variability did not differ between the 4 meters (p = 0.154 and 0.882 respectively), but within-session FEV(1) COV differed between meters (p = 0.009).

CONCLUSION:

PEF was marginally more sensitive to within-day variability than FEV(1) but was less repeatable. Overall, differences between the 4 meters were small, suggesting that all meters are clinically useful.

PMID:
19905927
DOI:
10.3109/02770900903229677
[Indexed for MEDLINE]

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