Infiltrating glomus tumor of uncertain malignant potential arising in the kidney

Hum Pathol. 2010 Jan;41(1):145-9. doi: 10.1016/j.humpath.2009.08.003. Epub 2009 Nov 6.

Abstract

Glomus tumors closely resemble the normal glomus body and have a predilection for skin and subcutaneous tissue. These tumors rarely present in visceral organs. We report a case involving the kidney. This glomus tumor displays typical cytology and immunohistochemical profile of glomus tumors elsewhere. However, this tumor is large, has a deep location and exhibits an infiltrative margin and increased mitotic activity. These features, by current definition, would suggest malignant behavior. However, the rarity of such an entity in the kidney highlights the need for caution and a diagnosis in a continuum between benignity and malignancy. To the best of our knowledge, this report is the first case of infiltrating glomus tumor or glomus tumor of uncertain malignant potential arising in the kidney.

Publication types

  • Case Reports

MeSH terms

  • Biomarkers, Tumor / analysis
  • Glomus Tumor / chemistry
  • Glomus Tumor / pathology*
  • Glomus Tumor / surgery
  • Humans
  • Kidney Neoplasms / chemistry
  • Kidney Neoplasms / pathology*
  • Kidney Neoplasms / surgery
  • Male
  • Middle Aged
  • Mitosis
  • Neoplasm Invasiveness
  • Treatment Outcome

Substances

  • Biomarkers, Tumor