Abstract
Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae, Escherichia coli, and Serratia marcescens were sequentially identified in a patient who underwent small bowel transplantation. Molecular typing and plasmid analysis suggested that the KPC gene was acquired by E. coli, most likely from K. pneumoniae, and was subsequently transferred to S. marcescens.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Anti-Bacterial Agents / therapeutic use
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Bacterial Proteins / genetics*
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Carbapenems / therapeutic use
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Drug Resistance, Bacterial / genetics
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Escherichia coli / genetics
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Female
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Gene Transfer, Horizontal / genetics*
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Humans
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Klebsiella Infections / drug therapy
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Klebsiella Infections / microbiology*
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Klebsiella pneumoniae / enzymology
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Klebsiella pneumoniae / genetics*
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Plasmids / genetics
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Polymerase Chain Reaction
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Serratia marcescens / genetics
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beta-Lactamases / genetics*
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Carbapenems
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beta-Lactamases
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carbapenemase