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J Leukoc Biol. 2010 Jan;87(1):107-16. doi: 10.1189/jlb.0809566. Epub 2009 Oct 30.

CD57+ T lymphocytes and functional immune deficiency.

Author information

1
Division of Hematology, Azienda Ospedaliera Santa Chiara, University of Pisa, via Roma, Pisa, Italy. dfocosi@tin.it

Erratum in

Abstract

CD57(+) expression in T lymphocytes has been recognized for decades as a marker of in vitro replicative senescence. In recent years, accumulating evidences have pointed on the utility of this marker to measure functional immune deficiency in patients with autoimmune disease, infectious diseases, and cancers. We review here the relevant literature and implications in clinical settings.

PMID:
19880576
DOI:
10.1189/jlb.0809566
[Indexed for MEDLINE]

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