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Nucleic Acids Res. 2010 Jan;38(Database issue):D280-2. doi: 10.1093/nar/gkp892. Epub 2009 Oct 30.

NNDB: the nearest neighbor parameter database for predicting stability of nucleic acid secondary structure.

Author information

1
Department of Chemistry and Center for RNA Biology, Box 0216, University of Rochester, Rochester, NY 14627-0216, USA.

Abstract

The Nearest Neighbor Database (NNDB, http://rna.urmc.rochester.edu/NNDB) is a web-based resource for disseminating parameter sets for predicting nucleic acid secondary structure stabilities. For each set of parameters, the database includes the set of rules with descriptive text, sequence-dependent parameters in plain text and html, literature references to experiments and usage tutorials. The initial release covers parameters for predicting RNA folding free energy and enthalpy changes.

PMID:
19880381
PMCID:
PMC2808915
DOI:
10.1093/nar/gkp892
[Indexed for MEDLINE]
Free PMC Article

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