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Cell. 2009 Oct 30;139(3):464-5. doi: 10.1016/j.cell.2009.10.008.

Pseudophosphatases: grab and hold on.

Author information

1
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. tonks@cshl.edu

Abstract

Catalytically inactive pseudophosphatases are able to signal in the absence of enzymatic activity. Analyzing the oocyte-to-zygote transition in the worm, Cheng et al. (2009) and Parry et al. (2009) now show how two pseudophosphatases, EGG-4 and EGG-5, can regulate signaling by the DYRK family kinase MBK-2.

PMID:
19879835
DOI:
10.1016/j.cell.2009.10.008
[Indexed for MEDLINE]
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