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Mutat Res. 1991 Jan;262(1):47-50.

Study of reproductive function in persons occupationally exposed to 2,4-dichlorophenoxyacetic acid (2,4-D).

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Hospital Regional Dr. Abel Ayerza, Marcos Juárez, Argentina.


We studied the reproductive function of 32 male farm sprayers who were exposed to 2,4-D. Sperm analysis was made after 4 days of sexual inactivity. Parameters analyzed were volume, sperm count, mobility and morphology. Exposure level was estimated by measuring the concentration of 2,4-D in the urine. Significant levels of asthenospermia, necrospermia and teratospermia were found in exposed workers compared with unexposed controls. Over time, asthenospermia and necrospermia diminished but the abnormal spermatozoa (teratospermia) continued.

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