Format

Send to

Choose Destination
See comment in PubMed Commons below
Appl Microbiol Biotechnol. 2010 Jan;85(4):893-9. doi: 10.1007/s00253-009-2262-7. Epub 2009 Oct 27.

Pentanol isomer synthesis in engineered microorganisms.

Author information

  • 1Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095, USA.

Abstract

Pentanol isomers such as 2-methyl-1-butanol and 3-methyl-1-butanol are a useful class of chemicals with a potential application as biofuels. They are found as natural by-products of microbial fermentations from amino acid substrates. However, the production titer and yield of the natural processes are too low to be considered for practical applications. Through metabolic engineering, microbial strains for the production of these isomers have been developed, as well as that for 1-pentanol and pentenol. Although the current production levels are still too low for immediate industrial applications, the approach holds significant promise for major breakthroughs in production efficiency.

PMID:
19859707
PMCID:
PMC2804790
DOI:
10.1007/s00253-009-2262-7
[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer Icon for PubMed Central
    Loading ...
    Support Center