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Curr Opin Otolaryngol Head Neck Surg. 2009 Dec;17(6):427-30. doi: 10.1097/MOO.0b013e328330dab6.

Botulinum toxin in the treatment of vocal fold nodules.

Author information

1
Centre for Voice and Swallowing, University of California, Davis, UC Davis Medical Centre, Sacramento, California 95817, USA. Jacqueline.Allen@ucdmc.ucdavis.edu

Abstract

PURPOSE OF REVIEW:

Promising new techniques in the management of vocal fold nodules have been developed in the past 2 years. Simultaneously, the therapeutic use of botulinum toxin has rapidly expanded. This review explores the use of botulinum toxin in treatment of vocal nodules and summarizes current therapeutic concepts.

RECENT FINDINGS:

New microsurgical instruments and techniques, refinements in laser technology, radiosurgical excision and steroid intralesional injections are all promising new techniques in the management of vocal nodules. Botulinum toxin-induced 'voice rest' is a new technique we have employed in patients with recalcitrant nodules. Successful resolution of nodules is possible with this technique, without the risk of vocal fold scarring inherent in dissection/excision techniques. Botulinum toxin usage is exponentially increasing, and large-scale, long-term studies demonstrate its safety profile.

SUMMARY:

Targeted vocal fold temporary paralysis induced by botulinum toxin injection is a new, well tolerated and efficacious treatment in patients with persistent vocal fold nodules.

PMID:
19858719
DOI:
10.1097/MOO.0b013e328330dab6
[Indexed for MEDLINE]

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