Abstract
The aim of this study was to determine the efficacy of a killed Salmonella vaccine and three live vaccines in preventing caecal colonisation of Hy-line Brown pullets by Salmonella Enteritidis PT 4. The lowest number of Salmonella-positive birds following the largest challenge (10(8) cfu) was recorded for live vaccine 1. However, birds treated with the killed vaccine had a significantly lower number of salmonellae in their caeca compared with both the control group and the other vaccine groups (P<0.05).
Publication types
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Comparative Study
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cecum / microbiology
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Chickens*
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Colony Count, Microbial / veterinary
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Drug Administration Schedule
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Euthanasia, Animal
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Female
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Poultry Diseases / prevention & control*
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Salmonella Infections, Animal / prevention & control*
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Salmonella Vaccines / administration & dosage
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Salmonella Vaccines / standards*
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Salmonella enteritidis / growth & development
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Salmonella enteritidis / immunology*
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United Kingdom
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Vaccines, Attenuated / standards
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Vaccines, Inactivated / standards
Substances
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Salmonella Vaccines
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Vaccines, Attenuated
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Vaccines, Inactivated