Salmonella colonisation of laying hens following vaccination with killed and live attenuated commercial Salmonella vaccines

Vet Rec. 2009 Oct 24;165(17):493-6. doi: 10.1136/vr.165.17.493.

Abstract

The aim of this study was to determine the efficacy of a killed Salmonella vaccine and three live vaccines in preventing caecal colonisation of Hy-line Brown pullets by Salmonella Enteritidis PT 4. The lowest number of Salmonella-positive birds following the largest challenge (10(8) cfu) was recorded for live vaccine 1. However, birds treated with the killed vaccine had a significantly lower number of salmonellae in their caeca compared with both the control group and the other vaccine groups (P<0.05).

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cecum / microbiology
  • Chickens*
  • Colony Count, Microbial / veterinary
  • Drug Administration Schedule
  • Euthanasia, Animal
  • Female
  • Poultry Diseases / prevention & control*
  • Salmonella Infections, Animal / prevention & control*
  • Salmonella Vaccines / administration & dosage
  • Salmonella Vaccines / standards*
  • Salmonella enteritidis / growth & development
  • Salmonella enteritidis / immunology*
  • United Kingdom
  • Vaccines, Attenuated / standards
  • Vaccines, Inactivated / standards

Substances

  • Salmonella Vaccines
  • Vaccines, Attenuated
  • Vaccines, Inactivated