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J Infect. 2010 Jan;60(1):79-82. doi: 10.1016/j.jinf.2009.09.017. Epub 2009 Oct 21.

Successful treatment of immune reconstitution inflammatory syndrome in Whipple's disease using thalidomide.

Author information

1
Université de la Méditerranée, Unité des Rickettsies, URMITE CNRS-IRD UMR 6236, Faculté de Médecine, 27 Bd Jean Moulin, 13385 Marseille cedex 05, France.

Abstract

A patient with classic Whipple's disease developed erythema nodosum leprosum-like lesions and fever one month after the beginning of an accurate therapy with trimethoprim-sulfamethoxazole. Immune reconstitution inflammatory syndrome was suspected, but corticosteroid therapy failed to improve the patient. Finally, thalidomide was used and successfully induced rapid improvement.

PMID:
19852981
DOI:
10.1016/j.jinf.2009.09.017
[Indexed for MEDLINE]

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