Format

Send to

Choose Destination
See comment in PubMed Commons below
Am Nat. 2009 Dec;174(6):E230-42. doi: 10.1086/645087.

Inverse-gene-for-gene infection genetics and coevolutionary dynamics.

Author information

1
School of Biological Sciences, University of Liverpool, Crown Street, Liverpool L697ZB, United Kingdom.

Abstract

The genetic basis of infection in host-parasite interactions has traditionally been considered within the framework of either gene-for-gene (GFG) or matching-allele models. We present an alternative model, termed inverse-gene-for-gene (IGFG), where pathogen infectiousness is determined by parasite recognition of host signals and/or receptors or where there is active host searching by parasites. We show that coevolutionary dynamics under IGFG are both qualitatively and quantitatively different from those of the GFG model, and we suggest that this new approach may be applicable to a range of important host-parasite systems that are not currently catered for by the existing frameworks.

PMID:
19852618
DOI:
10.1086/645087
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for University of Chicago Press
    Loading ...
    Support Center