Format

Send to

Choose Destination
See comment in PubMed Commons below
Am J Psychiatry. 1991 Jan;148(1):127-9.

Controlled comparison of buspirone and clomipramine in obsessive-compulsive disorder.

Author information

1
Laboratory of Clinical Science, NIMH, NIH, Bethesda, Md.

Abstract

Eighteen outpatients with obsessive-compulsive disorder were treated with either buspirone, a partial serotonin agonist, or clomipramine, a serotonin uptake inhibitor, in a double-blind, random-assignment study. Both drugs led to statistically significant and similar improvements in scores on the Yale-Brown Obsessive-Compulsive Rating Scale and other obsessive-compulsive and depression scales. This preliminary result warrants further exploration with a larger sample and other serotonergic agents.

PMID:
1984696
DOI:
10.1176/ajp.148.1.127
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Support Center