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Rhinology. 2009 Sep;47(3):297-300. doi: 10.4193/Rhin08.156.

The use of fibrin sealant as a glue for septoplasty and conchotomy.

Author information

1
Department of Otolaryngology, Head and Neck Surgery, Assaf Harofeh Medical Center, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel. vaimed@yahoo.com

Abstract

OBJECTIVE:

The aim of our study was to investigate glue properties of a fibrin sealant in cases of septoplasty and conchotomy.

DESIGN:

Double-blind prospective randomized study.

MATERIALS AND METHODS:

A study of 146 patients (80 M, 66 F) who underwent septoplasty and conchotomy was performed in Assaf Harofeh Medical Center Tzrifin, Israel. The patients were divided randomly into two groups: Group I (n = 74) underwent septoplasty with transseptal suturing, and conchotomy with glue as a haemostatic. Group II (n = 72) underwent septoplasty and conchotomy with glue as a haemostatic as well as septal cartilage and mucoperichodrial flaps sealant (no transseptal suturing). The glue was based on a concentrate of human clottable proteins and purified native human thrombin.

RESULTS:

Our results showed complete healing in both groups without significant differences. One late postoperative nasal bleeding occurred in group I, and none in group II.

CONCLUSION:

We conclude that the use of second-generation glue in endonasal surgery is well suited to stop nasal bleeding and seal intranasal flaps. Moreover, it might help to avoid transseptal suturing.

PMID:
19839254
DOI:
10.4193/Rhin08.156
[Indexed for MEDLINE]

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