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Cell Host Microbe. 2009 Oct 22;6(4):299-300. doi: 10.1016/j.chom.2009.09.009.

Autophagy, apoptosis, and the influenza virus M2 protein.

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1
Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, IL 60208-3500, USA.

Abstract

Viral subversion and inhibition of host cell autophagy has been documented for several viruses. In this issue of Cell Host & Microbe,Gannagé et al. (2009) show that the influenza virus M2 integral membrane protein blocks autophagosome maturation, significantly affecting host cell apoptosis.

PMID:
19837369
DOI:
10.1016/j.chom.2009.09.009
[Indexed for MEDLINE]
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