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BMC Pediatr. 2009 Oct 16;9:65. doi: 10.1186/1471-2431-9-65.

Evaluation of seasonal patterns of Kawasaki syndrome- and rotavirus-associated hospitalizations in California and New York, 2000-2005.

Author information

1
Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Vector-borne and Enteric Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, GA, USA. aho3@cdc.gov

Abstract

BACKGROUND:

Kawasaki Syndrome (KS) is an uncommon childhood disease with unknown etiology. It has been suggested that rotavirus infection may play a causative role in the development of KS.

METHODS:

To examine potential temporal associations between KS and rotavirus infection, seasonal patterns of KS- and rotavirus-associated hospitalizations among children in California and New York during 2000-2005 were compared.

RESULTS:

Rotavirus hospital admissions were markedly winter seasonal, with very few summer hospitalizations. KS hospitalizations occurred year-round but also peaked slightly during winter and spring.

CONCLUSION:

The strong winter seasonal pattern of rotavirus clearly differed from the year-round pattern of KS hospitalizations. While the present study cannot completely rule out rotavirus as having a role in the development of KS, other agents must be involved in the etiology of KS.

PMID:
19835612
PMCID:
PMC2768681
DOI:
10.1186/1471-2431-9-65
[Indexed for MEDLINE]
Free PMC Article

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