Non-invasive evaluation of liver cirrhosis using ultrasound

Clin Radiol. 2009 Nov;64(11):1056-66. doi: 10.1016/j.crad.2009.05.010. Epub 2009 Aug 14.

Abstract

Ultrasound (US) is essential in both assessment of the potentially cirrhotic liver and surveillance of selected patients with chronic hepatitis as liver biopsy can be misleading or inaccurate in up to 25% of cases. Various techniques are already in routine use, such as grey-scale imaging, Doppler US, and contrast-enhanced US (CEUS), while newer techniques such as elastography and hepatic vein transit time (HVTT) have the potential to exclude patients without significant fibrosis or cirrhosis; however, they are operator dependent and require specific software. Grey-scale imaging may demonstrate changes, such as volume redistribution, capsule nodularity, parenchymal nodularity, and echotexture changes. The Doppler findings in the hepatic and portal veins, hepatic artery, and varices allow assessment of liver cirrhosis. However, the operator needs to be aware of limitations of these techniques. Low mechanical index CEUS plays an important role in the assessment of complications of cirrhosis, such as hepatocellular carcinoma and portal vein thrombus. Optimized US technique is crucial for accurate diagnosis of the cirrhotic liver and its complications.

Publication types

  • Review

MeSH terms

  • Carcinoma, Hepatocellular / complications
  • Carcinoma, Hepatocellular / diagnostic imaging
  • Contrast Media
  • Elasticity Imaging Techniques / methods
  • Hepatic Artery / diagnostic imaging
  • Hepatic Veins / diagnostic imaging
  • Humans
  • Hypertension, Portal / complications
  • Hypertension, Portal / diagnostic imaging
  • Liver Cirrhosis / complications
  • Liver Cirrhosis / diagnostic imaging*
  • Liver Neoplasms / complications
  • Liver Neoplasms / diagnostic imaging
  • Portal Vein / diagnostic imaging
  • Ultrasonography / methods
  • Ultrasonography, Doppler, Color / methods

Substances

  • Contrast Media