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Cancer. 1977 Oct;40(4):1761-4.

Benign liver-cell adenoma associated with long-term administration of an androgenic-anabolic steroid (methandienone).


A 19-year-old man with paroxysmal nocturnal hemoglobinuria treated for 3 years with Methandienone was admitted to the hospital with hemoperitoneum due to the rupture of an hepatic tumor. Histology revealed that it was a benign liver cell adenoma, with a pathologic appearance and mode of clinical presentation closely resembling those of cases observed to develop in association to contraceptive steroids.

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