Format

Send to

Choose Destination
See comment in PubMed Commons below
Cell Metab. 2009 Oct;10(4):245-6. doi: 10.1016/j.cmet.2009.09.005.

A new wrinkle in the fold: hepcidin links inflammation to the unfolded protein response.

Author information

1
Department of Internal Medicine, University of Utah, Salt Lake City, UT 84132, USA.

Abstract

The unfolded protein response (UPR) coordinates translational and transcriptional changes triggered by unfolded proteins within the endoplasmic reticulum. Two recent papers (Oliveira et al., 2009; Vecchi et al., 2009) show that the UPR modulates transcription of the hormone hepcidin, which controls plasma iron levels and perhaps innate immunity.

PMID:
19808016
DOI:
10.1016/j.cmet.2009.09.005
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center