Format

Send to

Choose Destination
See comment in PubMed Commons below
Nat Rev Microbiol. 2009 Nov;7(11):775-86. doi: 10.1038/nrmicro2221. Epub 2009 Oct 6.

The trypanosome flagellar pocket.

Author information

1
Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, UK. mcf34@cam.ac.uk

Abstract

Trypanosomes are important disease agents and excellent models for the study of evolutionary cell biology. The trypanosome flagellar pocket is a small invagination of the plasma membrane where the flagellum exits the cytoplasm and participates in many cellular processes. It is the only site of exocytosis and endocytosis and part of a multiorganelle complex that is involved in cell polarity and cell division. Several flagellar pocket-associated proteins have been identified and found to contribute to trafficking and virulence. In this Review we discuss the contribution of the flagellar pocket to protein trafficking, immune evasion and other processes.

PMID:
19806154
DOI:
10.1038/nrmicro2221
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group
    Loading ...
    Support Center