Format

Send to

Choose Destination
Cell. 2009 Oct 2;139(1):212-212.e1. doi: 10.1016/j.cell.2009.08.009.

Enhanced SnapShot: Antibiotic inhibition of protein synthesis II.

Author information

1
University of Munich, Germany.

Abstract

The translational apparatus is one of the major targets for antibiotics in the bacterial cell. Antibiotics predominantly interact with the functional centers of the ribosome, namely the messenger RNA (mRNA)-transfer RNA (tRNA) decoding region on the 30S subunit, the peptidyltransferase center on the 50S subunit, or the ribosomal exit tunnel through which the nascent polypeptide chain passes during translation. Protein synthesis can be divided into three phases: initiation, elongation, and termination/recycling.

PMID:
19804764
DOI:
10.1016/j.cell.2009.08.009
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center