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Opt Lett. 2009 Oct 1;34(19):2933-5. doi: 10.1364/OL.34.002933.

Three-dimensional fluorescence optical tomography in small-animal imaging using simultaneous positron-emission-tomography priors.

Author information

1
Department of Biomedical Engineering, University of California, Davis, Davis, California 95616, USA. cqli@ucdavis.edu

Abstract

We propose three-dimensional fluorescence optical tomography imaging for small animals guided by simultaneous priors from positron emission tomography (PET). Using a sparsity regularization, the target prior from PET images was incorporated into the reconstruction algorithm for optical imaging. The method and algorithms are validated with numerical simulations and a phantom experiment performed on a combined optical-PET scanner based on a conical mirror geometry.

PMID:
19794772
PMCID:
PMC2856619
DOI:
10.1364/OL.34.002933
[Indexed for MEDLINE]
Free PMC Article

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