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Psychiatr Danub. 2009 Sep;21(3):382-5.

The comorbidity of bipolar disorder and cardiovascular diseases from pharmacotherapy perspective.

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University Psychiatric Clinic Rebro, Clinical Hospital Centre Zagreb, 10000 Zagreb, Croatia.


The heart and mind are intimately linked. Patients with severe mental disorders have increased mortality rates compared with the general population and the leading cause of premature death is cardiovascular disease (CVD). Despite their high prevalence and substantial medical impact, comorbidity between cardiac conditions and psychiatric illnesses frequently go undiagnosed and untreated. It is very interesting to investigate the impact of mental health on cardiac disease and what is the complex underlying mechanism that links these two conditions.

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