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Emerg Infect Dis. 2009 Sep;15(9):1347-50. doi: 10.3201/eid1509.090442.

Zika virus outside Africa.

Author information

1
Barcelona Centre for International Health Research, Barcelona, Spain. ned.hayes@cresib.cat

Abstract

Zika virus (ZIKV) is a flavivirus related to yellow fever, dengue, West Nile, and Japanese encephalitis viruses. In 2007 ZIKV caused an outbreak of relatively mild disease characterized by rash, arthralgia, and conjunctivitis on Yap Island in the southwestern Pacific Ocean. This was the first time that ZIKV was detected outside of Africa and Asia. The history, transmission dynamics, virology, and clinical manifestations of ZIKV disease are discussed, along with the possibility for diagnostic confusion between ZIKV illness and dengue.The emergence of ZIKV outside of its previously known geographic range should prompt awareness of the potential for ZIKV to spread to other Pacific islands and the Americas.

PMID:
19788800
PMCID:
PMC2819875
DOI:
10.3201/eid1509.090442
[Indexed for MEDLINE]
Free PMC Article
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