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Anal Chem. 2009 Oct 1;81(19):7870-5. doi: 10.1021/ac901154s.

Analysis of protein conformation and dynamics by hydrogen/deuterium exchange MS.

Author information

1
Northeastern University, Boston, MA 02115-5000, USA. j.engen@neu.edu

Abstract

Understanding as much as possible about proteins in the shortest amount of time has long been a goal of hydrogen exchange (HX) MS. Recent technological advances have led to improvements in the technique, but has this goal yet been achieved? (To listen to a podcast about this Feature, please go to the Analytical Chemistry Web site at pubs.acs.org/journal/ancham.).

PMID:
19788312
PMCID:
PMC2756691
DOI:
10.1021/ac901154s
[Indexed for MEDLINE]
Free PMC Article

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