[Raynaud's phenomenon; diagnosis and treatment]

Ned Tijdschr Geneeskd. 2009:153:B216.
[Article in Dutch]

Abstract

Primary Raynaud's phenomenon (RP) is a relatively common disorder. Most patients with primary RP have only mild symptoms and do not develop complications. Distinguishing primary from secondary RP is important with respect to complications, and for prognosis and treatment. Secondary RP mainly manifests as part of systemic connective tissue disease. About 13% of patients diagnosed initially as having primary RP develop a systemic disorder within the following few years. Both auto-immune serology including antinuclear antibodies (ANA), and capillaroscopy are important diagnostic tools if one suspects the existence or development of a systemic disorder. Calcium antagonists are the cornerstone of RP pharmacotherapy.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Antibodies, Antinuclear
  • Calcium Channel Blockers / therapeutic use*
  • Humans
  • Microscopic Angioscopy / methods
  • Raynaud Disease / complications
  • Raynaud Disease / diagnosis*
  • Raynaud Disease / drug therapy*

Substances

  • Antibodies, Antinuclear
  • Calcium Channel Blockers