Format

Send to

Choose Destination
J Pediatr. 2010 Jan;156(1):49-53.e1. doi: 10.1016/j.jpeds.2009.07.013.

Outcomes at age 2 years of infants < 28 weeks' gestational age born in Victoria in 2005.

Author information

1
Newborn Services, Royal Women's Hospital, Melbourne, Australia. lwd@unimelb.edu.au

Abstract

OBJECTIVE:

To determine the survival rates and neurosensory outcomes of infants born at gestational age 22-27 weeks in the state of Victoria in 2005 and compare theses data with those for similar infants born in the 1990s.

STUDY DESIGN:

This was a population-based study of all extremely preterm (22-27 weeks' gestational age) live births in Victoria in 2005 free of lethal anomalies and randomly selected term controls. Survival and quality-adjusted survival rates at age 2 years were determined relative to the controls, and results were compared with regional extremely preterm cohorts born in 1991-92 and 1997.

RESULTS:

Of 270 very preterm live births in 2005, 172 (63.7%) survived to 2 years, not significantly different from the survival rate of 69.6% for those born in 1997. Rates of severe developmental delay and severe disability were lower than in the very preterm survivors born in 1997. Quality-adjusted survival rates in the extremely preterm cohorts rose from 42.1% in 1991-92 to 55.1% in 1997, but did not increase in 2005 (53.4%).

CONCLUSIONS:

Survival rates for infants born at 22-27 weeks' gestational age have not increased since the late 1990s, but the neurosensory outcome in survivors has improved.

PMID:
19783004
DOI:
10.1016/j.jpeds.2009.07.013
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center