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Mol Cell. 2009 Sep 24;35(6):729-30. doi: 10.1016/j.molcel.2009.09.010.

Linking the cell cycle to histone modifications: Dot1, G1/S, and cycling K79me2.

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1
Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK. jane.mellor@bioch.ox.ac.uk

Abstract

In a recent issue of Molecular Cell, Schulze et al. (2009) described distinct distributions and regulation of Dot1-dependent methylation states at lysine 79 on histone H3 and showed cell-cycle regulation of K79 dimethylation on genes expressed during the G1/S phase.

PMID:
19782019
DOI:
10.1016/j.molcel.2009.09.010
[Indexed for MEDLINE]
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