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Lancet. 1990 Nov 10;336(8724):1167-71.

Changing epidemiology of group A streptococcal infection in the USA.

Author information

1
Respiratory Diseases Branch, Centers for Disease Control, Atlanta, Georgia 30333.

Abstract

To see whether changes in the epidemiology of group A streptococcal disease in the USA have been accompanied by a corresponding change in serotype distribution, epidemiological and M-typing and T-typing data for 5193 strains sent to the Centers for Disease Control, Atlanta, between 1972 and 1988 were analysed. The proportions of M-types 1, 3, and 18 increased significantly during the study period. These M-types were more likely to be invasive, to cause fatal infection, and to occur in a cluster of infections than were other types. By contrast, the proportions of M-types 4 and 12 decreased; they were less invasive and were less likely to be found in clusters than were other types. These data suggest that changes in the epidemiology of group A streptococcal disease may be related to changes in the distribution of M-types causing infection.

PMID:
1978035
DOI:
10.1016/0140-6736(90)92777-f
[Indexed for MEDLINE]

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