[Zolpidem dependence and withdrawal seizure]

Rev Med Liege. 2009 Jul-Aug;64(7-8):407-8.
[Article in French]

Abstract

Zolpidem is an imidazopiridine with hypnotic properties. Compared to benzodiazepines, zolpidem has a mechanism of action that is thought to reduce the risk of dependence or abuse. However, in the past 10 years, several cases of zolpidem abuse, dependence and withdrawal reactions have been described in the litterature. Here, we describe a case of dependence and withdrawal seizure.

MeSH terms

  • Citalopram / therapeutic use
  • Female
  • GABA Agonists / adverse effects
  • Humans
  • Hypnotics and Sedatives / administration & dosage
  • Hypnotics and Sedatives / adverse effects*
  • Mental Disorders / drug therapy
  • Pyridines / administration & dosage
  • Pyridines / adverse effects*
  • Risk Factors
  • Seizures / chemically induced*
  • Selective Serotonin Reuptake Inhibitors / therapeutic use
  • Substance Withdrawal Syndrome*
  • Substance-Related Disorders / etiology
  • Substance-Related Disorders / prevention & control
  • Treatment Outcome
  • Zolpidem

Substances

  • GABA Agonists
  • Hypnotics and Sedatives
  • Pyridines
  • Serotonin Uptake Inhibitors
  • Citalopram
  • Zolpidem