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Intensive Care Med. 2009 Dec;35(12):2130-4. doi: 10.1007/s00134-009-1663-5. Epub 2009 Sep 23.

Effect of closed endotracheal suction in high-frequency ventilated premature infants measured with electrical impedance tomography.

Author information

1
Department of Neonatology (H3-144), Emma Children's Hospital AMC, PO Box 22660, 1100 DD Amsterdam, The Netherlands.

Abstract

OBJECTIVE:

To determine the global and regional changes in lung volume during and after closed endotracheal tube (ETT) suction in high-frequency ventilated preterm infants with respiratory distress syndrome (RDS).

DESIGN:

Prospective observational clinical study.

SETTING:

Neonatal intensive care unit.

PATIENTS:

Eleven non-muscle relaxed preterm infants with RDS ventilated with open lung high-frequency ventilation (HFV).

INTERVENTIONS:

Closed ETT suction.

MEASUREMENTS AND RESULTS:

Changes in global and regional lung volume were measured with electrical impedance tomography. ETT suction resulted in an acute loss of lung volume followed by spontaneous recovery with a median residual loss of 3.3% of the maximum volume loss. The median stabilization time was 8 s. At the regional level, the lung volume changes during and after ETT suction were heterogeneous in nature.

CONCLUSIONS:

Closed ETT suction causes an acute, transient and heterogeneous loss of lung volume in premature infants with RDS treated with open lung HFV.

PMID:
19774364
PMCID:
PMC2779442
DOI:
10.1007/s00134-009-1663-5
[Indexed for MEDLINE]
Free PMC Article

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