Format

Send to

Choose Destination
AIDS Behav. 2010 Jun;14(3):580-9. doi: 10.1007/s10461-009-9615-1.

Using electronic drug monitor feedback to improve adherence to antiretroviral therapy among HIV-positive patients in China.

Author information

1
Center for International Health and Development, Boston University, Boston, MA, USA. lsabin@bu.edu

Abstract

Effective antiretroviral therapy (ART) requires excellent adherence. Little is known about how to improve ART adherence in many HIV/AIDS-affected countries, including China. We therefore assessed an adherence intervention among HIV-positive patients in southwestern China. Eighty subjects were enrolled and monitored for 6 months. Sixty-eight remaining subjects were randomized to intervention/control arms. In months 7-12, intervention subjects were counseled using EDM feedback; controls continued with standard of care. Among randomized subjects, mean adherence and CD4 count were 86.8 vs. 83.8% and 297 vs. 357 cells/microl in intervention vs. control subjects, respectively. At month 12, among 64 subjects who completed the trial, mean adherence had risen significantly among intervention subjects to 96.5% but remained unchanged in controls. Mean CD4 count rose by 90 cells/microl and declined by 9 cells/microl among intervention and control subjects, respectively. EDM feedback as a counseling tool appears promising for management of HIV and other chronic diseases.

PMID:
19771504
PMCID:
PMC2865631
DOI:
10.1007/s10461-009-9615-1
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Springer Icon for PubMed Central
Loading ...
Support Center